The Vaginal Microbial Signatures of Preterm Birth Delivery in Indian Women.

ABSTRACT:

Background

The incidence of preterm birth (PTB) in India is around 13%. Specific bacterial communities or individual taxon living in the vaginal milieu of pregnant women is a potential risk factor for PTB and may play an important role in its pathophysiology. Besides, bacterial taxa associated with PTB vary across populations.

Objective

Conduct a comparative analysis of vaginal microbiome composition and microbial genomic repertoires of women who enrolled in the Interdisciplinary Group for Advanced Research on Birth Outcomes - A DBT India Initiative (GARBH-Ini) pregnancy cohort to identify bacterial taxa associated with term birth (TB) and PTB in Indian women.

Methods

Vaginal swabs were collected during all three trimesters from 38 pregnant Indian women who delivered

SUBMITTER: Kumar S 

PROVIDER: S-EPMC8169982 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature