Ontology highlight
ABSTRACT:
SUBMITTER: Lima GMA
PROVIDER: S-EPMC8171072 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Lima Gustavo M A GMA Jagudin Elmir E Talibov Vladimir O VO Benz Laila S LS Marullo Costantino C Barthel Tatjana T Wollenhaupt Jan J Weiss Manfred S MS Mueller Uwe U
Acta crystallographica. Section D, Structural biology 20210514 Pt 6
Crystallographic fragment screening (CFS) has become one of the major techniques for screening compounds in the early stages of drug-discovery projects. Following the advances in automation and throughput at modern macromolecular crystallography beamlines, the bottleneck for CFS has shifted from collecting data to organizing and handling the analysis of such projects. The complexity that emerges from the use of multiple methods for processing and refinement and to search for ligands requires an ...[more]