Effect of spraying l-menthol on peristalsis resumption during endoscopic submucosal dissection of gastric tumors.

ABSTRACT:

Background and aim

l-Menthol has smooth muscle-relaxing and antiperistaltic effects. We examined its effectiveness against peristalsis resumption during endoscopic submucosal dissection (ESD) of gastric tumors.

Methods

We retrospectively examined clinical data of 485 patients (501 lesions) who underwent ESD for upper gastrointestinal tumors in 2017. We included 119 patients (127 lesions) in whom peristaltic movement resumed during ESD and l-menthol was applied; 366 patients (374 lesions) without l-menthol application were used as controls. Video recordings were reviewed to determine whether l-menthol suppressed peristalsis resumption.

Results

In cases with l-menthol application, 2 (2.9%), 36 (14.3%), and 89 (71.2%) lesions were found in the upper (U), middle (M), and

SUBMITTER: Ishiyama A 

PROVIDER: S-EPMC8171147 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature