Micrometer-scale transient ion transport for real-time pH assay in living rat brains.

ABSTRACT: Ion transport has been widely used for various applications such as sensing, desalination and energy conversion; however, nearly all applications are based on steady-state ion transport. Herein, we for the first time demonstrate the capability of transient ion transport for in vivo sensing with both high spatial (∼μm) and temporal (∼ms) resolution by using pH as the model target. Transient ion transport behavior (i.e., time-dependent ion current change) was observed by applying high-frequency pulse potential. Importantly, we proposed the ion distribution transient model for this time-dependent ion transport behavior. With this model, the temporal resolution of the as-developed pH microsensor based on ion current was improved to the ms level, thus satisfying the requirement of

SUBMITTER: Zhang K 

PROVIDER: S-EPMC8171349 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature