Kidney and Urinary Tract Involvement in Epidermolysis Bullosa: Is Routine Follow-Up Necessary?

ABSTRACT:

Background

Several renal and urinary tract complications have been reported in patients with epidermolysis bullosa.

Objective

This study investigated kidney and urinary tract involvement in patients with epidermolysis bullosa.

Patients and methods

Patients with epidermolysis bullosa in treatment at the Dermatology Unit were included in the study. Glomerular and tubular functions were investigated.

Results

The study included 16 patients (4 females, 12 males) of mean 11.1 years (SD = 8.1 years). Estimated GFR was normal in all patients except one with end-stage renal disease. Excluding this patient, the urinary albumin/creatinine ratio and the fractional excretion of sodium were normal. The mean beta-2 microglobulin/creatinine ratio was 278.8 μg/g, and it was abn

SUBMITTER: Cicek N 

PROVIDER: S-EPMC8172055 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature