Impact of Bleeding on Quality of Life in Patients on DAPT: Insights From TRANSLATE-ACS.

ABSTRACT:

Background

Prolonged dual antiplatelet therapy (DAPT) is recommended after an acute myocardial infarction (AMI) to reduce ischemic events but is associated with increased rates of major and minor bleeding.

Objectives

This study sought to determine the incidence of post-percutaneous coronary intervention (PCI) bleeding that occurs on contemporary DAPT and its impact on quality of life (QOL).

Methods

We studied 9,290 AMI patients treated with PCI and discharged alive between April 2010 and September 2012. Post-discharge bleeding was categorized according to the Bleeding Academic Research Consortium (BARC) definition. The primary outcome was the 6-month Euro QOL-5 Dimension (EQ-5D) index score (a measure of health utility); a secondary outcome was the EQ-5D visual analog

SUBMITTER: Amin AP 

PROVIDER: S-EPMC8172137 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature