Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

ABSTRACT: The development of vaccines to fight COVID-19 has been a remarkable medical achievement. However, this global immunization effort has been complicated by a rare vaccine-related outcome characterized by thrombocytopenia and thrombosis in association with platelet-activating anti-platelet factor 4 antibodies. In this Spotlight, we will discuss the recently described complication of vaccine-induced immune thrombotic thrombocytopenia (VITT) occurring in response to certain COVID-19 vaccines. Although information about this clinical condition is rapidly evolving, we will summarize our current understanding of VITT.

SUBMITTER: Arepally GM 

PROVIDER: S-EPMC8172307 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature