Age Effect on Incidence, Physical, and Psychiatric Comorbidity for Sudden Cardiac Death in Schizophrenia: Effet de l'age sur l'incidence, la comorbidite physique et psychiatrique de la mort cardiaque subite dans la schizophrenie.

ABSTRACT:

Objective

The pathogenesis of sudden cardiac death may differ between younger and older adults in schizophrenia, but evidence remains scant. This study investigated the age effect on the incidence and risk of the physical and psychiatric comorbidity for sudden cardiac death.

Methods

Using 2000 to 2016 data from the Taiwan National Health Insurance Research Database and Department of Health Death Certification System, we identified a national cohort of 170,322 patients with schizophrenia, 1,836 of whom had a sudden cardiac death. Standardized mortality ratios (SMRs) were estimated. Hazard ratios and population attributable fractions of distinctive comorbidities for sudden cardiac death were assessed.

Results

The SMRs of sudden cardiac death were all >1.00 across each a

SUBMITTER: Chen PH 

PROVIDER: S-EPMC8172351 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature