Interplay between sex determination cascade and major signaling pathways during Drosophila eye development: Perspectives for future research.

ABSTRACT: Understanding molecular mechanisms of sexually dimorphic organ growth is a fundamental problem of developmental biology. Recent quantitative studies showed that the Drosophila compound eye is a convenient model to study the determination of the final organ size. In Drosophila, females have larger eyes than males and this is evident even after correction for the larger body size. Moreover, female eyes include more ommatidia (photosensitive units) than male eyes and this difference is specified at the third larval instar in the eye primordia called eye imaginal discs. This may result in different visual capabilities between the two sexes and have behavioral consequences. Despite growing evidence on the genetic bases of eye size variation between different Drosophila species and strains, mech

SUBMITTER: Surkova S 

PROVIDER: S-EPMC8172476 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature