MRI-based radiomics as response predictor to radiochemotherapy for metastatic cervical lymph node in nasopharyngeal carcinoma.

ABSTRACT:

Objective

To establish and substantiate MRI-based radiomic models to predict the treatment response of metastatic cervical lymph node to radiochemotherapy in patients with nasopharyngeal carcinoma (NPC).

Methods

A total of 145 consecutive patients with NPC were enrolled including 102 in primary cohort and 43 in validation cohort. Metastatic lymph nodes were diagnosed according to radiologic criteria and treatment response was evaluated according to the Response Evaluation Criteria in Solid Tumors. A total of 2704 radiomic features were extracted from contrast-enhanced T₁ weighted imaging (CE- T₁WI) and T₂ weighted imaging (T₂WI) for each patient, and were selected to construct radiomic signatures for CE-

SUBMITTER: Xu H 

PROVIDER: S-EPMC8173687 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature