The occurrence of coronary artery lesions in Kawasaki disease based on C-reactive protein levels: a retrospective cohort study.

ABSTRACT:

Background

This study aimed to assess the occurrence of coronary artery lesions (CAL) in patients with Kawasaki disease (KD) according to serum C-reactive protein (CRP) levels.

Methods

This retrospective analysis was based on the nationwide survey of KD conducted in the Republic of Korea between 2015 and 2017. We enrolled 9131 patients and defined low (< 3 mg/dL) and high (≥3 mg/dL) CRP groups. Demographic data, clinical characteristics, z-scores, and scores based on the Japanese criteria for CAL were compared between the two groups. Logistic regression analysis was used to identify CAL risk factors.

Results

The low CRP group accounted for 23% of patients. The mean age at diagnosis was higher in high CRP group compared to the low CRP group (34.4 ± 24.9 vs 31.7 ± 24.8 

SUBMITTER: An HS 

PROVIDER: S-EPMC8173749 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature