Family History of Pulmonary Fibrosis Predicts Worse Survival in Patients With Interstitial Lung Disease.

ABSTRACT:

Background

A number of genetic markers linked to familial pulmonary fibrosis predict differential survival in interstitial lung disease (ILD) patients. Although genetic testing is not performed routinely for ILD, family history commonly is obtained and may inform outcome risk.

Research question

Does survival vary between patients with and without self-reported familial pulmonary fibrosis?

Methods

Family history was acquired systematically for consecutive ILD patients who consented to clinical registry enrollment at the University of Texas Southwestern and the University of California at Davis. Patients were stratified by idiopathic pulmonary fibrosis (IPF) and non-IPF ILD diagnosis and were substratified by presence or absence of familial pulmonary fibrosis, defined a

SUBMITTER: Cutting CC 

PROVIDER: S-EPMC8173755 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature