Evidence for Expanding Invasive Mediastinal Staging for Peripheral T1 Lung Tumors.

ABSTRACT:

Background

Guidelines recommend invasive mediastinal staging for patients with non-small cell lung cancer and a "central" tumor. However, there is no consensus definition for central location. As such, the decision to perform invasive staging largely remains on an empirical foundation.

Research question

Should patients with peripheral T1 lung tumors undergo invasive mediastinal staging?

Study design and methods

All participants with a screen-detected cancer with a solid component between 8 and 30 mm were identified from the National Lung Screening Trial. After translation of CT data, cancer location was identified and the X, Y, Z coordinates were determined as well as distance from the main carina. A multivariable logistic regression model was constructed to evaluate

SUBMITTER: DuComb EA 

PROVIDER: S-EPMC8173766 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature