N⁶-methyladenosine RNA modification regulates strawberry fruit ripening in an ABA-dependent manner.

ABSTRACT:

Background

Epigenetic mark such as DNA methylation plays pivotal roles in regulating ripening of both climacteric and non-climacteric fruits. However, it remains unclear whether mRNA m⁶A methylation, which has been shown to regulate ripening of the tomato, a typical climacteric fruit, is functionally conserved for ripening control among different types of fruits.

Results

Here we show that m⁶A methylation displays a dramatic change at ripening onset of strawberry, a classical non-climacteric fruit. The m⁶A modification in coding sequence (CDS) regions appears to be ripening-specific and tends to stabilize the mRNAs, whereas m⁶A around the stop codons and within the 3' untranslated regions is generally negatively correlated with the

SUBMITTER: Zhou L 

PROVIDER: S-EPMC8173835 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature