Ontology highlight
ABSTRACT:
SUBMITTER: Hines AD
PROVIDER: S-EPMC8174007 | biostudies-literature | 2021 May-Jun
REPOSITORIES: biostudies-literature
Hines Adam D AD van Swinderen Bruno B
eNeuro 20210501 3
Super-resolution microscopy provides valuable insight for understanding the nanoscale organization within living tissue, although this method is typically restricted to cultured or dissociated cells. Here, we develop a method to track the mobility of individual proteins in <i>ex vivo</i> adult <i>Drosophila melanogaster</i> brains, focusing on a key component of the presynaptic release machinery, syntaxin1A (Sx1a). We show that individual Sx1a dynamics can be reliably tracked within neurons in t ...[more]