Creation and Validation of a Novel Sex-Specific Mortality Risk Score in LVAD Recipients.

ABSTRACT: Background Prior studies have shown that women have worse 3-month survival after receiving a left ventricular assist device compared with men. Currently used prognostic scores, including the Heartmate II Risk Score, do not account for the increased residual risk in women. We used the IMACS (International Society for Heart and Lung Transplantation Mechanically Assisted Circulatory Support) registry to create and validate a sex-specific risk score for early mortality in left ventricular assist device recipients. Methods and Results Adult patients with a continuous-flow LVAD from the IMACS registry were randomly divided into a derivation cohort (DC; n=9113; 21% female) and a validation cohort (VC; n=6074; 21% female). The IMACS Risk Score was developed in the DC to predict 3-month mortality,

SUBMITTER: Nayak A 

PROVIDER: S-EPMC8174331 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature