Muscle stimulation in advanced idiopathic pulmonary fibrosis: a randomised placebo-controlled feasibility study.

ABSTRACT:

Objectives

To assess the acceptability of neuromuscular electrical stimulation (NMES) of the quadriceps muscles in people with idiopathic pulmonary fibrosis (IPF) and to identify whether a future definitive trial is feasible.

Design

A randomised, parallel, two-group, participant and assessor-blinded, placebo-controlled feasibility trial with embedded qualitative interviews.

Setting

Outpatient department, Royal Brompton and Harefield Hospitals.

Participants

Twenty-two people with IPF: median (25th, 75th centiles) age 76 (74, 82) years, forced vital capacity 62 (50, 75) % predicted, 6 min walk test distance 289 (149, 360) m.

Interventions

Usual care (home-based exercise, weekly telephone support, breathlessness management leaflet) with either placebo or ac

SUBMITTER: Nolan CM 

PROVIDER: S-EPMC8174518 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature