A meta-analysis on allergen-specific immunotherapy using MCT^® (MicroCrystalline Tyrosine)-adsorbed allergoids in pollen allergic patients suffering from allergic rhinoconjunctivitis.

ABSTRACT:

Background

The World Allergy Organization and the European Academy of Allergy and Clinical Immunology recommend to perform product-specific meta-analyses for allergen-specific immunotherapies because of the high degree of heterogeneity between individual products. This meta-analysis evaluates the efficacy and safety of Glutaraldehyde-modified and MCT^® (MicroCrystalline Tyrosine)-adsorbed allergoids (MATA).

Methods

The databases MEDLINE, LILACS, embase, LIVIVO, Web of Science and Google (Scholar) were searched for publications on MATA up to June 2019. Primary endpoint was the combined symptom and medication score (CSMS). Secondary endpoints were single scores, immunogenicity and improvement of allergic condition. Secondary safety endpoints were the occurrence of si

SUBMITTER: Becker S 

PROVIDER: S-EPMC8174800 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature