Aetiological testing compared with syndromic management for sexually transmitted infections in HIV-infected pregnant women in South Africa: a non-randomised prospective cohort study.

ABSTRACT:

Objective

To measure the frequencies of sexually transmitted infections (STIs) and adverse pregnancy outcomes among women receiving either aetiological testing or syndromic management for STIs.

Design

Non-randomised prospective cohort study.

Setting

Primary healthcare facilities in Tshwane, South Africa.

Population

HIV-infected pregnant women attending antenatal care services.

Methods

Participants were enrolled to receive aetiological testing using Xpert® CT/NG and Xpert® TV assays or standard syndromic management. Outcome data were collected at the postnatal care visit (≤30 days from delivery) and from maternity records. Enrolment gestational age-adjusted relative risk (aRR) was calculated.

Main outcome measures

STI prevalence at postnatal visit,

SUBMITTER: Peters R 

PROVIDER: S-EPMC8175473 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature