Urine Nitric Oxide Is Lower in Parents of Autistic Children.

ABSTRACT: Parents raising children with autism spectrum disorder (ASD) usually carry on their daily life under tremendous stress, but limited empirical research has been devoted to this population. It is known that parents' health status directly impacts therapeutic outcome of ASD children. As an important regulator in cardiovascular, nervous and immune systems, nitric oxide (NO) levels haven't been reported in parents of ASD children yet. In this study, we measured urine nitrite and nitrate from 43 ASD parents (ASD-P), and 43 healthy adults in the same range of age (Control) who didn't have any ASD descendants. Comparison between the ASD-P and Control groups showed that NO2- , NO3- , and NO2- / NO3- were all significantly lower in the ASD-P group. Analysis on the interaction effect of sex and group

SUBMITTER: Yao L 

PROVIDER: S-EPMC8175662 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature