Retinal Ganglion Cells-Diversity of Cell Types and Clinical Relevance.

ABSTRACT: Retinal ganglion cells (RGCs) are the bridging neurons that connect the retinal input to the visual processing centres within the central nervous system. There is a remarkable diversity of RGCs and the various subtypes have unique morphological features, distinct functions, and characteristic pathways linking the inner retina to the relevant brain areas. A number of psychophysical and electrophysiological tests have been refined to investigate this large and varied population of RGCs. Technological advances, such as high-resolution optical coherence tomography imaging, have provided additional tools to define the pattern of RGC involvement and the chronological sequence of events in both inherited and acquired optic neuropathies. The mechanistic insights gained from these studies, in parti

SUBMITTER: Kim US 

PROVIDER: S-EPMC8175861 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature