Preoperative nTMS and Intraoperative Neurophysiology - A Comparative Analysis in Patients With Motor-Eloquent Glioma.

ABSTRACT:

Background

The resection of a motor-eloquent glioma should be guided by intraoperative neurophysiological monitoring (IOM) but its interpretation is often difficult and may (unnecessarily) lead to subtotal resection. Navigated transcranial magnetic stimulation (nTMS) combined with diffusion-tensor-imaging (DTI) is able to stratify patients with motor-eloquent lesion preoperatively into high- and low-risk cases with respect to a new motor deficit.

Objective

To analyze to what extent preoperative nTMS motor risk stratification can improve the interpretation of IOM phenomena.

Methods

In this monocentric observational study, nTMS motor mapping with DTI fiber tracking of the corticospinal tract was performed before IOM-guided surgery for motor-eloquent gliomas in a prospec

SUBMITTER: Rosenstock T 

PROVIDER: S-EPMC8175894 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature