Self-Organization and Information Processing: From Basic Enzymatic Activities to Complex Adaptive Cellular Behavior.

ABSTRACT: One of the main aims of current biology is to understand the origin of the molecular organization that underlies the complex dynamic architecture of cellular life. Here, we present an overview of the main sources of biomolecular order and complexity spanning from the most elementary levels of molecular activity to the emergence of cellular systemic behaviors. First, we have addressed the dissipative self-organization, the principal source of molecular order in the cell. Intensive studies over the last four decades have demonstrated that self-organization is central to understand enzyme activity under cellular conditions, functional coordination between enzymatic reactions, the emergence of dissipative metabolic networks (DMN), and molecular rhythms. The second fundamental source of order i

SUBMITTER: De la Fuente IM 

PROVIDER: S-EPMC8176287 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature