Association of New Perioperative Benzodiazepine Use With Persistent Benzodiazepine Use.

ABSTRACT:

Importance

Increased use of benzodiazepines has resulted in increasing rates of misuse and adverse effects associated with these drugs. Little is known about the initial exposure and source of benzodiazepines among those who use them persistently.

Objective

To examine the frequency of use and persistent use of benzodiazepines among patients undergoing major and minor surgical procedures.

Design, setting, and participants

This cohort study included 2 509 599 adult patients who underwent 1 of 11 common surgical procedures in the United States from 2009 to 2017 and were recorded in the MarketScan database. The rates of perioperative and persistent benzodiazepine use were examined in benzodiazepine-naive patients. Data analysis was conducted from July to November 2020.

SUBMITTER: Wright JD 

PROVIDER: S-EPMC8176328 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature