The global gene expression outline of the bovine blastocyst: reflector of environmental conditions and predictor of developmental capacity.

ABSTRACT:

Background

Morphological evaluation of embryos has been used to screen embryos for transfer. However, the repeatability and accuracy of this method remains low. Thus, evaluation of an embryo's gene expression signature with respect to its developmental capacity could provide new opportunities for embryo selection. Since the gene expression outline of an embryo is considered as an aggregate of its intrinsic characteristics and culture conditions, we have compared transcriptome profiles of in vivo and in vitro derived blastocysts in relation to pregnancy outcome to unravel the discrete effects of developmental competence and environmental conditions on bovine embryo gene expression outlines. To understand whether the gene expression patterns could be associated with blastocyst develo

SUBMITTER: Salilew-Wondim D 

PROVIDER: S-EPMC8176733 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature