A panel of 8-lncRNA predicts prognosis of breast cancer patients and migration of breast cancer cells.

ABSTRACT:

Background

Breast cancer (BCa) is the most commonly diagnosed cancer and the leading cause of cancer death among females around the world. Recent studies have indicated that long non-coding RNAs (lncRNAs) can serve as an independent biomarker for diagnosis and prognosis in many types of cancer, including pancreatic adenocarcinoma, gastric cancer, liver cancer, and lung cancer. Previous studies have shown that many lncRNAs are associated with the occurrence and development of BCa. However, few studies have combined multiple lncRNAs to predict the prognosis of early-stage BCa patients.

Methods

Systematic and comprehensive analysis of data from The Cancer Genome Atlas (TCGA) was conducted to identify lncRNA signatures with prognostic value in BCa. Additionally, the relative exp

SUBMITTER: Zhu L 

PROVIDER: S-EPMC8177463 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature