Reporting of statistical sample size calculations in publications of trials on age-related macular degeneration, glaucoma and cataract.

ABSTRACT:

Background

Transparent and complete publications of randomised controlled trials (RCT) ought to comply with the guidelines of the CONSORT Statement, which stipulates sample size calculation as an important aspect of trial planning. The objective of this study was to analyse and compare the reporting of statistical sample size calculations in RCT papers on the treatment of age-related macular degeneration (AMD), glaucoma and cataract published in 2018.

Material and methods

This study comprises a total of 113 RCT papers (RCT-P) published in 2018 (AMD: 14, glaucoma: 28, cataract: 71), in English or German, and identified through an internet-based literature search in PubMed and EMBASE. The primary outcome measure of the study was the number of trials providing a complete descri

SUBMITTER: Tulka S 

PROVIDER: S-EPMC8177464 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature