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The Potential Role for Immunotherapy in Biochemically Recurrent Prostate Cancer.

ABSTRACT: Biochemically recurrent prostate cancer represents a stage of prostate cancer where conventional (continued on next page) computed tomography and technetium Tc 99m bone scan imaging are unable to detect disease after curative intervention despite rising prostate-specific antigen. There is no clear standard of care and no systemic therapy has been shown to improve survival. Immunotherapy-based treatments potentially are attractive options relative to androgen deprivation therapy due to the generally more favorable side-effect profile. Biochemically recurrent prostate cancer patients have a low tumor burden and likely lymph node-based disease, which may make them more likely to respond to immunotherapy.

SUBMITTER: Bilusic M

PROVIDER: S-EPMC8177734 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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The Potential Role for Immunotherapy in Biochemically Recurrent Prostate Cancer.

Bilusic Marijo M Einstein David J DJ Karzai Fatima H FH Dahut William L WL Gulley James L JL Aragon-Ching Jeanny B JB Madan Ravi A RA

The Urologic clinics of North America 20201101 4

Biochemically recurrent prostate cancer represents a stage of prostate cancer where conventional (continued on next page) computed tomography and technetium Tc 99m bone scan imaging are unable to detect disease after curative intervention despite rising prostate-specific antigen. There is no clear standard of care and no systemic therapy has been shown to improve survival. Immunotherapy-based treatments potentially are attractive options relative to androgen deprivation therapy due to the genera ...[more]

PMID: 33008496

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Gene expression profile of biochemically recurrent prostate cancer

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Project description: Not available

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| S-EPMC4234307 | biostudies-literature

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