Metal microdrive and head cap system for silicon probe recovery in freely moving rodent.

ABSTRACT: High-yield electrophysiological extracellular recording in freely moving rodents provides a unique window into the temporal dynamics of neural circuits. Recording from unrestrained animals is critical to investigate brain activity during natural behaviors. The use and implantation of high-channel-count silicon probes represent the largest cost and experimental complexity associated with such recordings making a recoverable and reusable system desirable. To address this, we have designed and tested a novel 3D printed head-gear system for freely moving mice and rats. The system consists of a recoverable microdrive printed in stainless steel and a plastic head cap system, allowing researchers to reuse the silicon probes with ease, decreasing the effective cost, and the experimental effort and

SUBMITTER: Voroslakos M 

PROVIDER: S-EPMC8177890 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature