Presentation and outcomes of adrenal ganglioneuromas: A cohort study and a systematic review of literature.

ABSTRACT:

Objective

To describe the presentation and outcomes of patients with adrenal ganglioneuromas (AGNs).

Design

Single-centre retrospective cohort study (1 January 1995 to 31 December 2019) and systematic review of literature (1 January 1980 to 19 November 2019).

Patients

Diagnosed with histologically confirmed AGN.

Measurements

Baseline clinical, imaging and biochemical characteristics, recurrence rates and mortality. Subgroup analysis was performed on tumours with histologic elements of ganglioneuroma and pheochromocytoma (ie composite tumours).

Results

The cohort study included 45 patients with AGN, 20 (44%) of which had composite tumours. Compared to pure AGN, patients with composite tumour were older (median age, 62.5 vs. 35 years, p < .001), had smalle

SUBMITTER: Dages KN 

PROVIDER: S-EPMC8178203 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature