Ontology highlight
ABSTRACT:
SUBMITTER: Juvekar V
PROVIDER: S-EPMC8178981 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Juvekar Vinayak V Lim Chang Su CS Lee Dong Joon DJ Park Sang Jun SJ Song Gyeong Ok GO Kang Hyuk H Kim Hwan Myung HM
Chemical science 20201106 1
Two-photon photodynamic therapy (TP-PDT) is a promising approach for the treatment of cancer because of its better penetration depth and superior spatial selectivity. Here, we describe an azo group containing cyclized-cyanine derivatives (<b>ACC1</b> and <b>ACC2</b>) as a two-photon activated, type I based photosensitizer (PS). These small-molecule and heavy atom-free organic dyes showed marked reactive oxygen species (ROS)-generating ability under physiological conditions, as well as fast loadi ...[more]