Retrograde sulfur flow from glucosinolates to cysteine in Arabidopsis thaliana.

ABSTRACT: Specialized (secondary) metabolic pathways in plants have long been considered one-way routes of leading primary metabolite precursors to bioactive end products. Conversely, endogenous degradation of such "end" products in plant tissues has been observed following environmental stimuli, including nutrition stress. Therefore, it is of general interest whether specialized metabolites can be reintegrated into primary metabolism to recover the invested resources, especially in the case of nitrogen- or sulfur-rich compounds. Here, we demonstrate that endogenous glucosinolates (GLs), a class of sulfur-rich plant metabolites, are exploited as a sulfur source by the reallocation of sulfur atoms to primary metabolites such as cysteine in Arabidopsis thaliana Tracer experiments using ^34<

SUBMITTER: Sugiyama R 

PROVIDER: S-EPMC8179156 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature