Effects of thiourea on the skull of Triturus newts during ontogeny.

ABSTRACT:

Background

In amphibians, thyroid hormone (TH) has a profound role in cranial development, especially in ossification of the late-appearing bones and remodeling of the skull. In the present study, we explored the influence of TH deficiency on bone ossification and resulting skull shape during the ontogeny of Triturus newt hybrid larvae obtained from interspecific crosses between T. ivanbureschi and T. macedonicus.

Methods

Larvae were treated with two concentrations of thiourea (an endocrine disruptor that chemically inhibits synthesis of TH) during the midlarval and late larval periods. Morphological differences of the cranium were assessed at the end of the midlarval period (ontogenetic stage 62) and the metamorphic stage after treatment during the late

SUBMITTER: Ajdukovic M 

PROVIDER: S-EPMC8179219 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature