Supramolecular-induced regiocontrol over the photochemical [4 + 4] cyclodimerization of NHC- or azole-substituted anthracenes.

ABSTRACT: Thanks to the impressive control that microenvironments within enzymes can have over substrates, many biological reactions occur with high regio- and stereoselectivity. However, comparable regio- and stereoselectivity is extremely difficult to achieve for many types of reactions, particularly photochemical cycloaddition reactions in homogeneous solutions. Here, we describe a supramolecular templating strategy that enables photochemical [4 + 4] cycloaddition of 2,6-difunctionalized anthracenes with unique regio- and stereoselectivity and reactivity using a concept known as the supramolecular approach. The reaction of 2,6-azolium substituted anthracenes H₄-L(PF₆)₂ (L = 1a-1c) with Ag₂O yielded complexes anti-[Ag₂

SUBMITTER: Bai S 

PROVIDER: S-EPMC8179318 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature