A photoswitchable strapped calix[4]pyrrole receptor: highly effective chloride binding and release.

ABSTRACT: A stiff-stilbene strapped calix[4]pyrrole receptor can be reversibly switched by light between a strong chloride-binding Z-isomer and a very weakly binding E-isomer. The light-induced switching process is monitored by UV-Vis and ¹H NMR spectroscopy and chloride binding is studied in detail using both ¹H NMR and ITC titrations in DMSO and MeCN. In DMSO, at millimolar concentrations, switching from a fully bound to an almost fully unbound state can be triggered. Quantification of the binding constants in MeCN reveals an extraordinary 8000-fold affinity difference between the Z- and E-isomer. Single crystal X-ray crystallographic analysis gives insight into the structure of the photogenerated E-isomer and the geometry of the chloride-bo

SUBMITTER: Villaron D 

PROVIDER: S-EPMC8179391 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature