Antibacterial, antifungal and antioxidant activities of whole plant chemical constituents of Rumex abyssinicus.

ABSTRACT:

Background

Antibiotic resistance has contributed to the burden of infectious diseases both in the hospital and community setting, and represents a great threat to public health. Previous studies have revealed the role of reactive oxygen species as intermediate mediators of tissue damage, following antibiotherapies, indicating the need of associating antioxidants to these treatments. Therefore, the present work was designed to study the antibacterial, antifungal and antioxidant activities of extracts and compounds from Rumex abyssinicus Jacq. (Polygonaceae), as well as to investigate the antibacterial mechanisms of action of the most effective agents.

Methods

The plant extracts were prepared by maceration in organic solvents followed by column chromatography of the EtOAc frac

SUBMITTER: Kengne IC 

PROVIDER: S-EPMC8180025 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature