Role of liver support systems in the management of post hepatectomy liver failure: A systematic review of the literature.

ABSTRACT:

Backgrounds/aims

Post-hepatectomy liver failure (PHLF) is a serious complication following liver resection, with limited treatment options, and is associated with high mortality. There is a need to evaluate the role of systems that support the function of the liver after PHLF.

Aims

The aim of this study was to review the literature and summarize the role of liver support systems (LSS) in the management of PHLF. Publications of interest were identified using systematically designed searches. Following screening, data from the relevant publications was extracted, and pooled where possible.

Findings

Systematic review identified nine studies, which used either Plasma Exchange (PE) or Molecular Adsorbent Recirculating System (MARS) as LSS after PHLF. Across all studies, th

SUBMITTER: Pufal K 

PROVIDER: S-EPMC8180400 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature