Incorporating Nutrition, Vests, Education, and Strength Training (INVEST) in Bone Health: Trial Design and Methods.

ABSTRACT:

Background

Achievement of 5-10% weight loss (WL) among older adults living with obesity considerably improves prognosis of health-related outcomes; however, concomitant declines in bone mineral density (BMD) limit overall benefit by increasing fracture risk. Declines in mechanical loading contribute to WL-associated BMD loss, with pilot data signaling the addition of external weight replacement (via weighted vest use) during intentional WL mitigates bone loss at weight bearing sites to a similar degree as resistance exercise training (RT). Definitive data in support of weighted vest use as a potential strategy to mitigate WL-associated bone loss in this population are needed.

Methods

In the Incorporating Nutrition, Vests, Education, and Strength Training (INVEST) in Bone Hea

SUBMITTER: Miller RM 

PROVIDER: S-EPMC8180512 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature