Study Protocol: A 2-Month Cross-Over Controlled Feeding Trial Investigating the Effect of Animal and Plant Protein Intake on the Metabolome and Cardiometabolic Health

ABSTRACT: Abstract

Objectives

A dietary shift in favor of plant protein (PP) sources over animal protein (AP) sources has been advocated for both sustainability and health reasons, this dietary transition being noticeably associated to decreased cardiovascular and diabetes risks. The differences in amino acid composition between PP and AP may have several effects on the metabolic pathways, and in turn health impacts, which are still poorly characterized. This project aims at characterizing, with a combination of “omics” approaches, the metabolic reorientations induced by a dietary shift from AP to PP sources and understanding their health effects in a population at cardiometabolic risk.

Methods

We will conduct a cross-over randomized feeding trial (NCT04236518) in 20 healthy overwe

SUBMITTER:  

PROVIDER: S-EPMC8180783 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature