Whole Wheat and Bran Cereal Affects Microbiome Stability

ABSTRACT: Abstract

Objectives

Health outcomes in previous fiber intervention studies have been variable, potentially due to differences in gut microbiome composition. This study aimed to determine if the effect of fiber intervention on the microbiome differs by initial microbiome or the quantity of fiber provided.

Methods

This study was designed as a randomized, un-blinded, cross-over trial of fiber cereal dosage. The cross-over design tested the effect of two 2-week long interventions with a High (28g) and Low (14g) level of daily supplemental fiber from whole wheat and bran cereal. Analysis was also completed on the overall study as a single arm, non-randomized, intervention of fiber cereal. The study enrolled 31 healthy adults. The microbiome was assessed at baseline and after i

SUBMITTER:  

PROVIDER: S-EPMC8181604 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature