Local ablative therapy of brain metastasis from non-small cell lung cancer: benefits and limitations.

ABSTRACT: Brain metastases (BMs) are the most common intracranial tumors and non-small cell lung cancer (NSCLC) are responsible for BM more than any other solid tumor. Its frequency is increasing due to of the availability of new imaging techniques, earlier diagnosis and improvement in treatment techniques and survival rates. NSCLC patients with BM represent heterogeneous prognostic group. The possibility of better prognostic stratification associated with more systemic therapy options and imaging and radiation technology advances have led to an increment of evaluation and indication of local ablative radiotherapy. The definite increment in quality of life and the potential overall survival (OS) benefit of its indication must be balanced with eventual higher risk of brain disseminated disease when w

SUBMITTER: de Azevedo Rosas F 

PROVIDER: S-EPMC8182539 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature