The prognostic utility of the histologic subtype of stage I lung adenocarcinoma may be diminished when using only the invasive component to determine tumor size for tumor node metastasis (TNM) staging.

ABSTRACT:

Background

Histologic subtypes were considered prognostic factors in early-stage lung adenocarcinoma in the 7^th edition of the tumor node metastasis (TNM) staging system (TNM-7). However, the T-staging system has changed and now measures only the size of the invasive component to determine tumor size. The aim of this study was to determine whether the histologic subtype is still a prognostic factor in the 8^th edition of the TNM staging system (TNM-8).

Methods

From 2010 to 2017, 788 patients who underwent curative surgery for stage I lung adenocarcinoma according to TNM-8 were analyzed retrospectively. Survival rates were compared among predominant patterns of adenocarcinoma. Prognostic factors were analyzed according to risk factors for recurrence in st

SUBMITTER: Sung YE 

PROVIDER: S-EPMC8182542 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature