Protective ventilation and outcomes of critically ill patients with COVID-19: a cohort study.

ABSTRACT:

Background

Approximately 5% of COVID-19 patients develop respiratory failure and need ventilatory support, yet little is known about the impact of mechanical ventilation strategy in COVID-19. Our objective was to describe baseline characteristics, ventilatory parameters, and outcomes of critically ill patients in the largest referral center for COVID-19 in Sao Paulo, Brazil, during the first surge of the pandemic.

Methods

This cohort included COVID-19 patients admitted to the intensive care units (ICUs) of an academic hospital with 94 ICU beds, a number expanded to 300 during the pandemic as part of a state preparedness plan. Data included demographics, advanced life support therapies, and ventilator parameters. The main outcome was 28-day survival. We used a multivariate Co

SUBMITTER: Ferreira JC 

PROVIDER: S-EPMC8182738 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature