Temporal phylogeny and molecular characterization of echovirus 30 associated with aseptic meningitis outbreaks in China.

ABSTRACT:

Background

An outbreak of aseptic meningitis occurred from June to August 2016, in Inner Mongolia Autonomous Region, China.

Methods

To determine its epidemiological characteristics, etiologic agent, and possible origin, specimens were collected for virus isolation and identification, followed by molecular epidemiological analysis.

Results

A total of 363 patients were clinically diagnosed from June 1st to August 31st 2016, and most cases (63.1%, n = 229) were identified between June 22nd and July 17th, with children aged 6 to 12 years constituting the highest percentage (68.9%, n = 250). All viral isolates from this study belonged to genotype C of echovirus 30 (E30), which dominated transmission in China. To date, two E30 transmission lineages have been identified in C

SUBMITTER: Tian X 

PROVIDER: S-EPMC8182919 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature