Growth hormone receptor gene is related to root length and tooth length in human teeth.

ABSTRACT:

Objectives

To examine the relationship between tooth length and growth hormone receptor (GHR) gene variants in a healthy Japanese population.

Materials and methods

The subjects consisted of 193 Japanese adults (69 men, 124 women), aged 13 to 56 years. Genomic DNA was extracted from saliva and genotyped GHR rs6184 and rs6180 variants using the Taqman genotyping. Computed tomography (CT) images were acquired using a dental cone-beam CT scanner and reconstructed using open-source OsiriX medical image processing software. The maxillary (upper; U) and mandibular (lower, L) central incisors (1), lateral incisors (2), canines (3), first premolars (4), second premolars (5), first molars (6), and second premolars (7) were evaluated. Teeth were assessed for crown height (CH), root len

SUBMITTER: Hikita Y 

PROVIDER: S-EPMC8183145 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature