Population diversity of cardiovascular outcome trials and real-world patients with diabetes in a Chinese tertiary hospital.

ABSTRACT:

Background

Recent cardiovascular outcome trials (CVOTs) changed the therapeutic strategy of guidelines for type 2 diabetes. We compared the characteristics of patients from real-world hospital settings with those of participants in recent pragmatic randomized trials.

Methods

This electronic medical record (EMR)-based retrospective observational study investigated the data of patients with diabetes from inpatient and outpatient settings in West China Hospital of Sichuan University from January 1, 2011, to June 30, 2019. We identified patients meeting the inclusion criteria of a pragmatic randomized trial (EMPA-REG OUTCOME) based on EMRs and compared their baseline characteristics with those of the trial participants. The cutoff for the clinical significance of each characteri

SUBMITTER: Zhou YL 

PROVIDER: S-EPMC8183749 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature