Noninvasive electrocardiographic assessment of ventricular activation and remodeling response to cardiac resynchronization therapy.

ABSTRACT:

Background

Cardiac resynchronization therapy (CRT) produces acute changes in electric resynchronization that can be measured noninvasively with electrocardiographic body surface mapping (ECGi). The relation between baseline acute electrophysiology metrics and their manipulation with CRT and reverse remodeling is unclear.

Objective

To test (ECGi) derived parameters of electrical activation as predictors of volumetric response to CRT.

Methods

ECGi was performed in 21 patients directly following CRT implant. Activation parameters (left ventricular total activation time [LVtat], global biventricular total activation time [VVtat], global left/right ventricular electrical synchrony [VVsync], and global left ventricular dispersion of activation times [LVdisp]) were measured

SUBMITTER: Jackson T 

PROVIDER: S-EPMC8183873 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature