Cumulative Deficits Frailty Index Predicts Outcomes for Solid Organ Transplant Candidates.

ABSTRACT: Despite comprehensive multidisciplinary candidacy assessments to determine appropriateness for solid organ transplantation, limitations persist in identifying candidates at risk of adverse outcomes. Frailty measures may help inform candidacy evaluation. Our main objective was to create a solid organ transplant frailty index (FI), using the cumulative deficits model, from data routinely collected during candidacy assessments. Secondary objectives included creating a social vulnerability index (SVI) from assessment data and evaluating associations between the FI and assessment, waitlist, and posttransplant outcomes.

Methods

In this retrospective cohort study of solid organ transplant candidates from Toronto General Hospital, cumulative deficits FI and SVI were created from data collec

SUBMITTER: Varughese RA 

PROVIDER: S-EPMC8183975 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature