An ultrasound-derived stroke risk score to identify patients at high risk of stroke.

ABSTRACT:

Background

To develop an ultrasound-derived stroke risk (USR) score combining plaque stiffness, surface morphology and lumen narrowing to evaluate the risk of stroke in patients with asymptotic carotid stenosis.

Methods

We developed the USR score in a prospective study of symptomatic and asymptomatic patients with ipsilateral carotid lumen narrowing. Multivariable analysis was performed to identify parameters associated with ischemic events, and a USR score was constructed based on the observed β coefficient. The discrimination performance of the USR score was assessed using receiver operating characteristic (ROC) curves. Twenty iterations of 5-fold cross-validation were used for internal validation.

Results

We derived the USR score (range, 0-7) by incorporating plaqu

SUBMITTER: Li Y 

PROVIDER: S-EPMC8184428 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature