A nomogram for predicting brain metastasis in patients with de novo stage IV breast cancer.

ABSTRACT:

Background

Brain metastasis (BM) is a very serious event in patients with breast cancer. The aim of this study was to establish a nomogram to predict the risk of BM in patients with de novo stage IV breast cancer.

Methods

We gathered female patients diagnosed with de novo stage IV breast cancer between 2010 and 2015 from the Surveillance, Epidemiology, and End Results (SEER) database. After randomly allocating the patients to the training set and verification set, we used univariate and multivariate logistic regression to analyze the relationship between BM and clinicopathological features. Finally, we developed a nomogram which was validated by the analysis of calibration curve and receiver operating characteristic curve.

Results

Of 7,154 patients with de n

SUBMITTER: Sun MS 

PROVIDER: S-EPMC8184439 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature